The Human Behavioral Pharmacology Laboratory

Weafer, J, D Gallo, H. de Wit (2016) Alcohol effects on encoding and consolidation of memory for emotional stimuli.  Journal of Studies on Alcohol and Drugs. 77:86-94. PMCID: PMC4711324

Van den Berg, S.M., …H. de Wit,.. D.I. Boomsma (60 authors) (2016) Extraversion and common genetic variants: GWAS meta-analysis results from the Genetics of Personality Consortium.  Behavior Genetics. 46:170-82. doi: 10.1007/s10519-015-9735-5.  PMCID: PMC4751159

Miller, MA, AK Bershad, H de Wit. Drug effects on responses to emotional facial expressions: Recent findings.  Behavioural Pharmacology. 26:571-9. PMCID: PMC4905685

Bershad, AK, JJ Weafer, MG Kirkpatrick, MC Wardle, MA Miller, H de Wit (2016)  Oxytocin receptor gene variation predicts subjective responses to MDMA. Social Neuroscience. 17:1-8. PMID: 26787430 

Bershad, AK, H de Wit. (2016) Effects of buprenorphine on responses to social stimuli in healthy adults.  Psychoneuroendocrinology. 63:43-9. PMCID: PMC4695221

Wardle, MC, AK Bershad, H de Wit (2016) Naltrexone alters the processing of social stimuli in healthy adults.  Social Neuroscience. 22:1-13. PMID: 26710657 PMCID: PMC4958027

Kirkpatrick MG, Goldenson NI, Kapadia N, Kahler CW, de Wit H, Swift RM, McGeary JE, Sussman S, Leventhal AM. (2016) Emotional traits predict individual differences in amphetamine-induced positive mood in healthy volunteers. Psychopharmacology. 233:89-97. PMCID: PMC4703469

Wardle, MC, BA Marcus, H de Wit (2015) A preliminary investigation of individual differences in subjective responses to d-amphetamine, alcohol, and delta-9-tetrahydrocannabinol using a within-subjects randomized trial. PloS One. 10:e0140501. PMCID: PMC4626040

Temple, JL, AM Ziegler, H de Wit, C Martin (2015) Caffeine effects on subjective responses are influenced by caffeine dose, sex, and pubertal stage. Journal of Caffeine Research. 5:167-175. PMCID: PMC4663646

VanderBroek, L, J Acker, AA Palmer, H de Wit, J MacKillop (2016)  Interrelationships between family history of substance misuse, impulsive delay discounting, and substance use. Psychopharmacology 233:39-48. PMID: 26395990  PMCID: PMC4830143

Hanlon, EC, E Tasali, R Leproult, KL Stuhr, E Doncheck, H de Wit, CJ Hillard, E Van Cauter (2016) Sleep restriction enhances the daily rhythm of circulating levels of endocannabinoid 2-arachidonoylglycerol. Sleep. 39(3):653-664. PMCID: PMC4763355

Mayo, L, H de Wit (2016) Acquisition of conditioned responses to a novel alcohol-paired cue in social drinkers. Journal of Studies on Alcohol and Drugs, 77, 317-26. PMID: 26997190 

Smith, CT, J Weafer, RL Cowan, RM Kessler, AA Palmer, H de Wit, DH Zald (2016) Individual differences in timing of peak positive subjective responses to d-amphetamine: relationship to pharmacokinetics and physiology. J of Psychopharmacology, 30, 330-43.  PMID: 26880226

Cavallo, J, N Ruiz, H de Wit (2016) Extinction of conditioned responses to methamphetamine-associated stimuli in healthy humans. Psychopharmacology 233, 2489-502. PMCID: PMC4909474

Weafer, J, D Gallo, H de Wit (2016) Effect of alcohol on encoding and consolidation of memory for alcohol-related images.  Alcoholism: Clinical and Experimental Research 40, 1540-7. PMCID: PMC4930409

Kirkpatrick, M.G. and H. de Wit (2015) MDMA: a social drug in a social context. Psychopharmacology, 232, 1155-1163. PMCID: PMC4339498

Clark, C.M., D.G. Frye, M.C. Wardle, G.J. Norman, H. de Wit (2015) Acute effects of MDMA on autonomic cardiac activity and their relation to subjective pro-social and stimulant effects.  Psychophysiology, 52:429-35. PMCID: PMC4634859

Gorka, S.M., Fitzgerald, D.A., de Wit, H., & Phan, K.L. (2014) Cannabinoid modulation of amygdala subregion functional connectivity to social signals of threat. The International Journal of Neuropsychopharmacology 28, 18. PMCID: PMC4360235

Gorka, S., D. Fitzgerald, M. Angstadt, H. de Wit, K.L. Phan (2014)  Opioid modulation of resting-state anterior cingulate cortex functional connectivity. Journal of Psychopharmacology, 28, 1115-24 PMID: 25237122 

Weafer, J., J. DeArcangelis, H. de Wit (2015) Sex differences in behavioral impulsivity in at-risk and non-risk drinkers.  Frontiers in Neuroscience 6, 72. PMCID: PMC4429551
Weafer, J., S.H. Mitchell, H. de Wit  (2015) Recent translational findings on impulsivity in relation to drug abuse.  Current Addiction Reports, 1, 289-300. PMCID: PMC4323183

Bershad, A.K., J. H. Jaffe, E. Childs, H. de Wit (2015) Opioid partial agonist buprenorphine dampens responses to psychosocial stress in humans. Psychoneuroendocrinology, 52, 281-8. PMCID: PMC4297554

Ballard, M.E., J. Weafer, D. Gallo, H. de Wit (2015)  Methamphetamine-induced enhancement of emotional memory formation in humans: Encoding vs consolidation. PlosOne, 10. PMCID: PMC4332474

Mayo, L., H. de Wit (2015) Acquisition of responses to a methamphetamine-associated cue in healthy humans: self-report, behavioral, and psychophysiological measures. Neuropsychopharmacology, 40, 1734-41. PMID: 25601231 [PubMed - in process].

Kirkpatrick, M.G., A.W. Delton, T.E. Robertson, H. de Wit (2015) Prosocial effects of MDMA:  A measure of generosity. Journal of Psychopharmacology, 29, 661-8. PMID: 25735993 

Bershad, A.K., M.G. Kirkpatrick, J.A. Seiden, H. de Wit (2015) Effects of acute doses of prosocial drugs methamphetamine and alcohol on plasma oxytocin levels. Journal of Clinical Psychopharmacology, 35, 308-12. PMCID: PMC4414800

Baggott, M.J., M.G. Kirkpatrick, G. Bedi, H. de Wit. (2015) Intimate insight: MDMA changes how people talk about significant others.  J. Psychopharmacology, 29, 669-77. PMCID: PMC4698152

Yarosh, H.L., S.A. Meda, H. de Wit, A.B. Hart, G.D. Pearlson (2015) Multivariate analysis of subjective responses to d-amphetamine in healthy volunteers finds novel genetic pathway associations. Psychopharmacology, 2781-94. PMCID: PMC4504822

Hanlon, E.C., E. Tasali, R. Leproult, K Stuhr, E. Doncheck, H. de Wit, C.J. Hillard, E. Van Cauter (2015)  Circadian rhythm of circulating levels of endocannabinoid 2-arachidonoylglycerol. The Journal of Clinical Endocrinology & Metabolism, 100, 200-6. PMID: 25368979 

De Moor, M.H.M.,  … H. de Wit,… D.I. Boomsma (60 authors) (2015) Meta-analysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder.  JAMA Psychiatry, 72, 642-50. PMCID: PMC4667957 

Ballard, E., D. Gallo, H. de Wit (2014) Amphetamine increases errors during episodic memory retrieval. Journal of Clinical Psychopharmacology, 34, 85-92 PMC4244906

Frye, C.G., M.C. Wardle, G.J. Norman, H. de Wit (2014) MDMA decreases the effects of simulated social rejection.  Pharmacology, Biochemistry and Behavior, 117, 1-6. PMC3910346

Weafer, J., D.Gallo, H. de Wit (2014) Amphetamine fails to alter cued recollection of emotional images: Study of encoding, retrieval, and state-dependency. Plos One 9 PMC3937372

Kirkpatrick, M.G., S. M. Francis, R. Lee, H. de Wit, S. Jacob (2014)  Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans. Psychoneuroendocrinology, 46, 23-31. PMC4088952

Childs, E., H. de Wit (2014) Regular exercise is associated with emotional resilience to acute stress in healthy adults. Frontiers in Physiology 5, 161. PMC4013452

Wardle, M., D. Fitzgerald, M. Angstadt, C. Rabinak, H. de Wit, K.L. Phan (2014) Effects of oxycodone on brain responses to emotional images.  Psychopharmacology. PMID: 24800897 [PubMed - as supplied by publisher]  

Wardle, M.C., H. de Wit (2014)  MDMA alters emotional processing and facilitates social interaction.  Psychopharmacology.  PMC4194242

Hart, A.B., E.R. Gamazon, B. E. Engelhardt, P. Sklar, C. Hultman, Pa. F. Sullivan, B. Neale, S.V. Faraone, Psychiatric Genomics Consortium: ADHD Subgroup, H. de Wit, N. J. Cox, A.A. Palmer (2014)  Genetic variation associated with the euphorigenic effects of d-amphetamine is also associated with diminished risk for schizophrenia and ADHD. Proceedings of the National Academy of Sciences, 111, 5968-73.  PMC4000861

Clark, D.B., H. de Wit, W. Iacono (2014) ADHD, Impulsivity and Substance Abuse: Methods, Results and Implications. Experimental and Clinical Psychopharmacology, 22, 141-3. PMC4141644

Kirkpatrick, M., R. Lee, M. Wardle, S. Jacob, H. de Wit (2014) Effects of MDMA and intranasal oxytocin on social and emotional processing. Neuropsychopharmacology. 39, 1654-63. PMC4088952

Childs, E., T.L. White, H. de Wit (2014) Personality traits modulate subjective and physiological responses to stress. Behavioural Pharmacology 25, 493-502. PMC4119514

Kirkpatrick, M.G., M.J. Baggott, J.E. Mendelson, G.P. Galloway, M.E Liechti, C.M Hysek, H. de Wit. (2014) MDMA effects consistent across controlled laboratory settings. Psychopharmacology 231, 3899–3905.   PMC4161650

Weafer, J. A. Burkhardt, H. de Wit (2014) Sweet taste liking associated with impulsive behaviors in humans. Frontiers in Behavioral Neuroscience, 8, 228. PMC4060557

Weafer, J. and H. de Wit. (2014) Sex differences in impulsive action and impulsive choice.  Addictive Behaviors 39, 1573-9 PMC4012004

Wardle, M.C., M.G. Kirkpatrick, H. de Wit (2014) “Ecstasy” as a social drug: MDMA preferentially affects responses to emotional stimuli with social content.  Social Cognitive and Affective Neuroscience 9, 1076-81. PMCID: PMC4127030

Bedi, G, G. Cecchi, D.F. Slezak, F. Carrillo, M. Sigma, H. de Wit (2014) A window into the intoxicated mind:  Speech as an index of psychoactive drug effects.  Neuropsychopharmacology, 39, 2340-8. PMCID: PMC4138742